By S. Rehncrona (auth.), F. Cohadon, V. V. Dolenc, J. Lobo Antunes, H. Nornes, J. D. Pickard, H.-J. Reulen, A. J. Strong, N. de Tribolet, C. A. F. Tulleken (eds.)
As an addition to the eu postgraduate education process for younger neurosurgeons we started to put up in 1974 this sequence of Advances and Technical criteria in Neurosurgery which used to be later backed by means of the ecu organization of Neurosurgical Societies. This sequence was once first mentioned in 1972 at a mixed assembly of the Italian and German Neurosurgical Societies in Taormina, the founding fathers of the sequence being Jean Brihaye, Bernard Pertuiset, Fritz Loew and Hugo KrayenbtihI. hence have been demonstrated the rules of eu co operation that have been born from the ecu spirit, flourished within the eu organization, and feature all through been linked to this sequence. the truth that the English language is easily with a purpose to turning into the overseas medium at eu medical meetings is a brilliant asset when it comes to mutual knowing. accordingly we have now made up our minds to post all contributions in English, whatever the local language of the authors. All contributions are submitted to the complete editorial board prior to publi cation of any quantity. Our sequence isn't meant to compete with the courses of unique clinical papers in different neurosurgical journals. Our goal is, relatively, to give fields of neurosurgery and comparable parts during which very important contemporary advances were made. The contributions are written by way of experts within the given fields and represent the 1st a part of every one volume.
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Extra resources for Advances and Technical Standards in Neurosurgery
1992, Tontsch et al. 1994). 01igodendrocytes injected into the spinal cord may migrate quite long distances to exert their effect and, recently improvement in nerve fibre conduction time was demonstrated in fibres remyelinated in this way (Utzschneider 1994). These data strongly favour the possibility of future glial cell transplantation therapy in these currently intractable and devastating disorders. General Conclusions Of greatest importance is the central fact that neural transplantation to the human central nervous system is possible and that grafts can integrate, survive and improve lost neurological functions for extended time periods.
Since no estimates of graft survival were conducted it is impossible to conclude whether the improvements reported are results of graft function or not. With respect to the small number of patients improved and the fact that the mesencephalic tissue used for grafting had gestational ages above 11 weeks it seems highly unlikely that the transplantation method used resulted in surviving, dopamine producing and pysiologically integrated grafts. Three transplanting centres (Lund, Tampa and Paris) have reported PET-scan data that clearly indicate graft survival (Lindvall et al.
Most brain cell grafting procedures and experiments have centered around neuronal grafting. However, the very promising results with glial cell grafting should be emphasized. This research aims at remyelinating fibres to reanimate function in demyelination disorders like multiple sclerosis (MS), adrenoleucodystrophy (ALD) and adrenomyeloneuropathy (AMN). Transplanted oligodendrocytes have been shown to remyelinate widespread areas of demyelinated fibers in lysolecithin and X-ray induced focal lesions as well as in mutant mice, rats and dogs (Blakemore and Franklin 1991, Baron-Van Evercooren 1992, Duncan et al.
Advances and Technical Standards in Neurosurgery by S. Rehncrona (auth.), F. Cohadon, V. V. Dolenc, J. Lobo Antunes, H. Nornes, J. D. Pickard, H.-J. Reulen, A. J. Strong, N. de Tribolet, C. A. F. Tulleken (eds.)